Anti-ZW10 peptide抗體,著絲粒蛋白抗體* 返回列表頁

     Anti-ZW10 peptide抗體,著絲粒蛋白抗體*產(chǎn)品介紹：The mitotic checkpoint ensures that chromosomes are divided equally between daughter cells and is a primary mechanism preventing the chromosome instability often seen in aneuploid human tumors. This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase. It is part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. In mitotic human cells ZW10 resides in a complex with Rod and Zwilch, whereas another ZW10 partner, Zwint-1, is part of a separate complex of structural kinetochore components including Mis12 and Ndc80-Hec1. Zwint-1 is critical for recruiting ZW10 to unattached kinetochores. Depletion from human cells demonstrates that the ZW10 complex is essential for stable binding of a Mad1-Mad2 complex to unattached kinetochores. Thus, ZW10 functions as a linker between the core structural elements of the outer kinetochore and components that catalyze generation of the mitotic checkpoint-derived "stop anaphase" inhibitor. 

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保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時(shí)4°C存儲(chǔ)，保質(zhì)期六個(gè)月，*存儲(chǔ)時(shí)建議分裝為10ul以上小包裝-20°C存儲(chǔ)，并避免反復(fù)凍融，保質(zhì)期一年。

產(chǎn)品名稱 Anti-ZW10 peptide抗體,著絲粒蛋白抗體*

產(chǎn)品編號 BYK-1938R

英文名稱 ZW10 peptide
中文名稱 著絲粒蛋白抗體
別    名 Centromere/kinetochore protein zw10; Centromere/kinetochore protein zw10 homolog; HZW 10; HZW10; Kinetochore associated homolog; KNTC1AP; MGC149821; Zeste White 10; Zeste white 10 homolog; ZW-10; ZW 10; centromere/kinetochore protein; ZW 10 kinetochore associated homolog; ZW10 (Drosophila) homolog centromere/kinetochore protein; ZW10 homolog centromere/kinetochore protein (Drosophila); ZW10 homolog centromere/kinetochore protein; ZW10 kinetochore associated homolog; ZW10_MOUSE.
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞分化     

抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
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